Powered by machine learning-based probe design and a new production process, the SureSelect Human All Exon V8 spans a 35.1 Mb target region of the human genome with an efficient end-to-end design size of only 41.6 Mb. The panel delivers excellent enrichment performance, as well as efficient and cost-effective exome sequencing. In addition, the panel is manufactured in large scale to provide consistent results for many years.
The SureSelect Human All Exon V8 is compatible with the legacy SureSelectXT target enrichment system, as well as the streamlined SureSelectXT HS2, SureSelectXT HS, SureSelectXT Low Input, and SureSelectQXT library preparation and target enrichment systems, which feature a fast, 90-minute hybridization protocol and a single-day workflow. The V8 exome workflow is natively supported by the Bravo Automated Liquid Handling platform for high-throughput sample preparation, and the Magnis NGS Prep system for complete, walkaway automation. The sequencing data can be readily analyzed using Alissa Interpret for efficient variant interpretation and reporting, providing an end-to-end exome sequencing solution.