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Jumpcode Genomics

San Diego,  CA 
United States
  • Booth: 125

How many of your sequencing dollars are wasted on information you don’t need? 

Jumpcode Genomics allows you to overcome the limitations of biology. With our CRISPRclean™ technology, you can harness the specificity of CRISPR-Cas9 to remove unwanted and uninformative molecules from next-generation sequencing (NGS) libraries so that you can shift your sequencing power for deeper coverage and improved signal.

Ready to learn more? Attend our Lightning talk, CoLab, or schedule a meeting with our experts.

  • Platform presentation by Dr. Alden Y. Huang (UCLA): Oct 20 at 11:30 AM EST
    • See how Dr. Huang pushed the limits of CRISPRclean as a large scale Cas9 mediated depletion of highly abundant transcripts to expand the interpretable genome and improve the diagnostic yield of clinical RNA-Seq
  • Live CoLab presentation: Oct 20 at 3:00 PM EST
    • Hear about how we built CRISPRclean technology as a scalable CRISPR-based depletion of highly abundant RNA transcripts to increase sensitivity of low expressed transcripts in RNA-Seq
  • Live Lightning talk: Oct 22 at 12:00 PM EST
    • Learn about the CRISPRclean products portfolio and NGS applications


  • CRISPRclean Stranded Total RNA Prep rRNA Depletion
    CRISPRclean technology harnesses the specificity of CRISPR-Cas9 to degrade abundant, uninformative sequences. Combined with a stranded total RNA library prep, CRISPRclean workflow improves sensitivity to detect low-expressing transcripts in RNA-Seq....

  • Biological samples are complex, often containing contaminating nucleic acids from other species. Ribosomal RNA (rRNA) or even common bacterial transcripts are significantly over expressed relative to transcripts of interest. Removal of contaminating or high expressing transcripts will enable better detection of biologically relevant signals. Currently Jumpcode Genomics offers products to enable the following applications:

    Whole transcriptome profiling: Remove mammalian rRNA to shift sequencing depth to detection of low abundance RNA’s.

    Microbiome: Removal of bacterial rRNA form over 212 bacterial species, covering all phyla in a single depletion reaction. Increase the number of bacterial species detectable by 3-4X.

    Infectious Disease Surveillance: Deplete both human and bacterial rRNA sequences from complex biological samples for greater sequencing coverage of viral and bacterial pathogens, and identify low expressing human transcripts related to immune response.

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