Fluent Biosciences

• Booth: 1912

Our mission is to accelerate the understanding of biology and disease through simple, cost effective and scalable single cell solutions for every laboratory.

 Press Releases

• Fluent BioSciences launches industry’s most accessible, cost-effective and scalable technology (PIPseq™) to accelerate adoption of single-cell RNA sequencing in any laboratory (Aug 26, 2022)

  Priced as low as $300 per reaction, the T2 and T20 kits enable any researcher to immediately access the power of single-cell transcriptomics with no capital investment

  WATERTOWN, Mass., June 23, 2022 /PRNewswire/ — Fluent BioSciences, a biotechnology company focused on making single-cell analysis simple and accessible to every researcher, announced the launch of two new breakthrough products for 3′ single-cell RNA analysis.  Scaled to efficiently fit diverse experimental demands, PIPseq T2 and T20 v3.0 kits capture up to 2,000 and 20,000 single cells or nuclei per reaction, respectively. In addition, Fluent announces early access for higher scale T200 kits, to enable studies up to 200,000 cells in a single sample, as well as an Epitope Sequencing Kit for multi-omics applications. 

  “Fluent BioSciences is breaking down the barriers to entry in the single-cell market with our ground-breaking PIPseq technology and products,”  stated Sepehr Kiani, co-founder, and CEO of Fluent BioSciences. “On the heels of a very successful early access phase, the upgraded v3.0 kits offer improved biological resolution in a benchtop kit to truly enable single cell analysis in every laboratory across a range of applications from low cell diversity projects to comprehensive solid tissue studies at unprecedented scale, flexibility and cost efficiency.”

  Fluent’s Pre-templated Instant Partition (PIPs) platform uniquely enables sensitive single cell analysis with simple, easily implemented workflows. PIPseq also does not require expensive instrumentation or complex microfluidic consumables, providing highly cost-effective single cell analysis, which is especially timely as researchers seek to execute ambitious science in a challenging funding environment.  PIPseq is priced at $300 per T2 reaction and $900 per T20 reaction, allowing any researcher to access the power of single-cell transcriptome analysis.

  Fluent has been collaborating with a leading neuroscience researcher, Dr. Shane Liddelow, Assistant Professor, Department of Neuroscience at NYU Langone, New York City to evaluate brain tissue samples.  “The ease with which we have been able to generate large numbers of single-cells for challenging neuronal samples is amazing,” stated Dr. Liddelow. “Sequencing quality, including genes detected, doublet errors, and mitochondrial contamination levels are exceptional, and on par with other methods, and I have no doubt that PIPseq will be an impactful addition to the laboratory repertoire for any researcher.” Researchers are invited to contact Fluent to learn more about the early access programs or applying PIPseq to their biological question of interest.

• Fluent BioSciences and NanoCellect announce joint collaboration to improve resolution of single-cell RNA sequencing analysis of rare cell populations (Aug 26, 2022)

  Watertown, MA, June 17, 2022 – Fluent BioSciences, a biotechnology company focused on making single-cell analysis simple and accessible to every researcher, and NanoCellect Biomedical, Inc., a leader in the development and manufacturing of innovative and affordable solutions for cell sorting, jointly announced a collaboration to improve resolution and efficiency of single-cell RNA sequencing (scRNA-seq) analysis of rare cell populations. 

  Single-cell researchers are increasingly requiring scalable, flexible and accessible workflow solutions, and the combination of cell sorting on the NanoCellect platform followed by scRNA-seq on a novel, instrument-free platform for scRNA-seq based on Pre-templated Instant Partitions (PIPseq™) from Fluent can be a highly efficient solution for a wide range of single cell applications across oncology, immunology and neuroscience.

  “For single-cell sequencing to truly become mainstream researchers need benchtop solutions that fit their diverse experimental needs rather than compromising the science with complex, expensive, and inflexible platforms.” stated Sepehr Kiani Ph.D., co-founder, and CEO of Fluent BioSciences. “I am very pleased that Fluent and NanoCellect are able to leverage and combine the unique advantages of our respective technologies to expand the use of single-cell RNA sequencing for rare cell populations.”

  “Reliable and reproducible sample preparation is critically important to the scRNAseq workflow” stated Jose Morachis, Ph.D., President and co-founder at NanoCellect.  “NanoCellect’s WOLF® and WOLF G2® Cell Sorters can function as a valuable step in the scRNA-seq workflow by isolating only cells of interest while removing dead cells and debris, thus improving scRNA-seq resolution of rare cell populations of interest and overall sequencing data quality.”

  About Fluent BioSciences

  Fluent’s mission is to accelerate the understanding of single-cell biology through accessible, affordable, and scalable solutions for every researcher.  Our breakthrough PIPseq™ technology enables extremely sensitive and unbiased preparation of proteins and nucleic acids for a broad range of applications.

  For more information, visit https://www.fluentbio.com/

  About NanoCellect Biomedical

  NanoCellect is committed to empowering every scientist to make discoveries one cell at a time, by ensuring high cell viability required to advance cell-based research.  We develop and deliver microfluidic based solutions that are affordable, compact, and easy-to-use. Our expanding portfolio of instruments and consumables enable biomedical scientists to analyze and sort cells required for drug discovery, single cell-omics, cloning, antibody discovery, and basic research.For more information, visit https://nanocellect.com/

• Fluent BioSciences expands access to industry’s most flexible and scalable technology (PIPseq) to enable sensitive single-cell transcriptome analysis in any laboratory (Aug 26, 2022)

  Watertown, MA., May 5, 2022 – Fluent BioSciences, a biotechnology company focused on making single-cell analysis simple and accessible to every researcher, announced expanded early access to two new products for 3′ single-cell RNA analysis. Scaled to efficiently and effectively meet diverse experimental demands, PIPseqTM T2 and T20 kits capture up to 2,000 and 20,000 single cells per reaction, respectively. Fluent is actively engaged with leading researchers in diverse fields including neuroscience, drug discovery, and cancer biology to demonstrate the unique advantages to experimental flexibility and scalability afforded by PIPseq. 

  “We continue to execute on our mission to accelerate the understanding of biology and disease through accessible, affordable, and scalable solutions”, stated Sepehr Kiani, co-founder, and CEO of Fluent BioSciences. “I am very pleased that we have been able to leverage Fluent’s unique, instrumentation-free scRNA-seq platform to rapidly introduce an order-of-magnitude increase in cell capture compared to our initial T2 kits. We are poised for rapid development and deployment of new tools to address the diversity of emerging single-cell applications.”

  Fluent has been excited to collaborate with Dr. Zev Gartner, Professor of Pharmaceutical Chemistry at the University of California, San Francisco to evaluate cellular diversity in human breast tissue. “We required a single-cell RNA-seq platform with a simple workflow suitable for rapid analysis of clinical specimens, that scales from small to large numbers of cells, and meets our data quality metrics”, stated Dr. Gartner. “Tissues analyzed using the T2 and T20 kits have exceeded our expectations.” White papers detailing these early studies are available at www.fluentbio.com, and researchers are invited to contact Fluent to learn more about applying PIPseq to their biological question of interest.

  About Fluent BioSciences

  Fluent BioSciences is a privately funded biotechnology company with a mission to accelerate the understanding of biology and disease through accessible, affordable, and scalable solutions for every laboratory from research to the clinic.  Fluent’s breakthrough Pre-templated Instant Partitions (PIPseq™) technology facilitates near-instantaneous self-assembly of individual cells or molecules into millions of uniform partitions without the need for complex instrumentation or expensive consumables. This powerful platform enables extremely sensitive and unbiased preparation of proteins and nucleic acids for a broad range of applications including single-cell RNA sequencing (scRNA-seq).