Jumpcode Genomics  

RNA samples frequently contain up to 90% ribosomal RNA. Transcriptome sequencing without removing these overabundant rRNA sequences reduces sequencing capacity and makes it harder to detect lower expressing, biologically relevant transcripts. See how CRISPRclean can help your research with effective rRNA removal.

Improve your discovery of high-value and biologically interesting transcripts with CRISPRclean today. Click here to learn more.

Traditionally, single cell data processing incorporates certain filtering and normalization steps prior to cell clustering and downstream interpretation. Instead of removing those reads in-silico, CRISPRclean removes those reads in-vitro ahead of sequencing, redistributing 50% sequencing clusters to unique biologically relevant transcripts—allowing you to maximize UMI and gene sensitivity.

CRISPRclean leverages Cas9 depletion and a specifically designed guide set to remove reads that are filtered before secondary analysis. CRISPRclean Single Cell RNA Boost Kit gives you the ability to cut through the noise with minimal impact on your workflow, and maximum confidence in your single cell RNA seq results.

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Our CRISPRclean High Expressing RNA Depletion kit removes the highest expressing transcripts in-vitro ahead of sequencing, redistributing ~70%* sequencing reads to unique biologically relevant transcripts—allowing you to maximize detection of low expressing transcripts or rare isoforms.

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