Chiesi Global Rare Diseases  

Discover Alpha-Mannosidosis was created to increase awareness and understanding of alpha-mannosidosis, an ultra-rare genetic disease that impacts between 1 in 500,000 and 1 in 1,000,000 children and adults worldwide.

Alpha-mannosidosis has a wide variety of symptoms across many organ systems, but timely diagnosis can make all the difference. Helping healthcare professionals, parents, and patients recognize symptoms of this disease is a key goal of the Discover Alpha-Mannosidosis program.

In addition to assisting with diagnosis by providing a diagnostic algorithm, Discover Alpha-Mannosidosis has created information about:

• Disease phenotype and genotype—and what those findings mean for patients
• The importance of genetic testing to identify alpha-mannosidosis
• Distinctive alpha-mannosidosis symptoms in patients of varying ages
• Life with alpha-mannosidosis
• Educational and supportive resources

Visit discoveralphamannosidosis.com/hcp/ to learn more.

References available upon request.

Soaring new possibilities in Fabry disease

Rethink FabryTM is dedicated to bringing the facts about Fabry disease, a rare genetic condition, to light. Estimated to impact between 1 in 3859 and 1 in 8454, Fabry is now known to significantly affect both male and female patients with symptoms ranging across a wide variety of organ systems in the body.

Although Fabry is now better understood than it once was, our work is far from over. Many challenges, from daily symptoms to long-term difficulties, still exist. In addition, Fabry may still be underdiagnosed—despite the fact that 1 diagnosis can lead to the identification of ~5 more family members with Fabry.

Rethink FabryTM is a comprehensive tool designed to support healthcare professionals as well as patients and their loved ones through a Fabry diagnosis, treatment, and life with Fabry, by providing information about:

• Diagnosing Fabry
• The importance of genetic testing for family members of Fabry patients
• Fabry symptoms in male and female patients—and their unique presentations
• Meaningful steps to help manage Fabry
• Fabry resources

Visit hcp.rethinkfabry.com to learn more.

References available upon request.