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Past, Present, and Future of Chiral Separations
Friday, March 12, 2021: 1:30 PM - 4:40 PM
Speaker(s)
Description
The Past, Present, and Future of Chiral Separations symposium features five experts who will discuss key historical advances, current state-of-the-art, and perspectives on the future of chiral chromatography. Presentations will cover topics related to column and stationary phase development and instrumentation, along with analytical and production-scale applications of chiral chromatography.
Additional Info
Presentations:
- Session Number: S18-01
- Friday, March 12, 1:30 PM - 2:05 PM
Chiral/enantiomeric separations play a vital role in academic and industrial research. Pharmaceutical, agricultural sciences, and other regulatory bodies heavily depend on chiral analyses. Enantiomeric separations have a rich history of trials tribulations and triumphs spanning more than five decades. Originally, most of the research enantiomeric separations was focused into the...
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- Session Number: S18-02
- Friday, March 12, 2:05 PM - 2:40 PM
Separation of enantiomers has become part of the daily activity in the pharmaceutical industry. The process of enantiomeric separation has become easier due to the number of chiral columns existing on the market. While the number of chiral columns has made method development for enantiomeric separations easier, the process of...
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- Session Number: S18-03
- Friday, March 12, 2:40 PM - 3:15 PM
The first preparative enantioseparations were performed over 30 years ago. Since that time preparative chiral chromatography has evolved to become a critical technique in pharmacetuical discovery and development. The past 30 years have seen technological advances that have allowed a wide range of racemates to be resolved from the mg...
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- Session Number: S18-04
- Friday, March 12, 3:30 PM - 4:05 PM
Professor William H. Pirkle (1934-2018) made a profound impact on modern chemistry by inventing and popularizing widely used techniques for the analysis and purification of enantiomers, contributions that paved the way for the subsequent advances in the discovery, development, and manufacture of enantiopure pharmaceuticals, agrochemicals, and specialty chemicals. Pirkle’s pioneering...
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- Session Number: S18-05
- Friday, March 12, 4:05 PM - 4:40 PM
Many molecules are developed and evaluated during early stages of drug discovery. The objective of Medicinal chemists is to design and synthesize molecules that will not only bind with high affinity to the target protein active site but also have good physicochemical properties. To achieve this objective, these molecules will...
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