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Analytical Challenges of Cannabinoid Testing in Toxicology
Thursday, March 11, 2021: 10:30 AM - 11:05 AM
Speaker(s)
Description
With the advent of liquid chromatography-tandem mass spectrometry (LC-MS/MS), analytical sensitivity has improved for cannabinoid testing in toxicology. However, challenges remain with regards to matrix effects, availability of reference standards, lengthy hydrolysis steps, limited specimen volume, and complex matrices. Sample preparation remains the most important consideration for cannabinoid testing and will be reviewed for traditional and emerging matrices. More recently, the popularity of cannabinoid products containing cannabidiol (CBD) and Δ8-tetrahydrocannabinol (Δ8-THC) created new analytical challenges. In particular, compound conversion and separation of isomers will be discussed. In order to better understand cannabinoid analyses and data interpretation, analytical challenges must be considered and assessed as the demand for cannabinoid identification and quantification continues to increase.
Track(s)
Additional Info
Keywords: Please select up to 4 keywords ONLY:
Clinical/Toxicology,CBD
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