Roche Sequencing & Life Science  

Indianapolis,  IN 
United States
http://ashg.roche.com
  • Booth: 701

At Roche Sequencing, we continue to build upon the Roche legacy of innovation by simplifying workflows, lowering barriers to routine sequencing, and increasing access to genomic data. Our evolving suite of products spans the NGS workflow from sample isolation and preparation through data analysis and final reporting, helping you to answer important questions in genetics, cancer genomics, gene expression, and beyond.

Produce high-quality sequencing libraries from DNA or RNA with our suite of KAPA Library Preparation Kits. Each kit generates high-quality libraries for analysis on Illumina sequencing platforms and is packaged in an easy-to-use format featuring robust enzymes created with our directed evolution technology.

Focus your sequencing resources by combining KAPA DNA Library Preparation Kits with our hybrid-capture target enrichment solutions; we offer panels for the analysis of the whole human exome, specific disease-associated regions, or the genomic regions of your choice.

In addition to providing you with a broad selection of industry-leading sequencing solutions, Roche is also dedicated to providing you with technical expertise, scientific support, and guidance you can depend on.  No matter your sequencing destination, you can be sure we’re with you every step of the way.

Brands: Roche, KAPA, SeqCap, MagNA Pure & AVENIO


 Products

  • Roche’s NEW target enrichment solution†
    Roche's new target enrichment portfolio combines new probe technology with Roche's strong design expertise for enriching regions of interest before sequencing.

    †Product in development. Not yet available for sale in the US.
    ...

  • The KAPA NGS sample prep portfolio now includes new probes for target enrichment, optimizing the efficiency of sequencing and sample prep.  The new probes offer greater coverage uniformity, target coverage, and probe fidelity compared to SeqCap EZ.*

    New whole exome panel:

    • Has a target size of ~43 Mb*
    • Includes 387 SNPs for sample-intrinsic tracking*
    • Covers regions in the CCDS, RefSeq, Ensembl, Gencode and ClinVar databases*

    New custom design probes:

    • Leverage the new HyperDesign tool, a user-friendly and intuitive design resource. Online access 24/7 and our expert designers provide flexible design options.

    New updated HyperCap workflow:

    • Combines the new probes with KAPA Library Prep Kits for a workflow that is even faster and more automation-friendly
    • Includes new KAPA HyperPure Beads and the soon-to-be-launched KAPA Universal Adapters with KAPA Unique Dual-Indexed Primer mixes

      *Data on file
      Product in development. Not yet available for sale in the US.

  • KAPA HyperPrep & HyperPlus Kits for DNA library
    High-performance KAPA HyperPrep and HyperPlus Kits kits offer flexible fragmentation options, optional PCR-free workflows, robust performance with low-quality samples, and convenient master-mix formats.*

    *Data on file....

  • KAPA HyperPrep

    • Start with mechanically sheared input DNA
    • Generate high-quality libraries in 2-3 hours from a wide range of sample types, including FFPE samples and cfDNA
    • Reduce bias with PCR-free workflows from lower input amounts─ ideal for WGS
    • Improve sequence coverage and library complexity in workflows with PCR
    • Automate library prep with validated scripts

    KAPA HyperPlus

    • Adjust fragment size with tunable, low-bias enzymatic fragmentation
    • Generate high-quality libraries in 1.5–3 hours from a wide range of sample types, amounts, and GC contents
    • Achieve industry-leading conversion rates and library complexity*, particularly for FFPE DNA
    • Reduce bias with PCR-free workflows from lower input amounts
    • Improve sequence coverage and library complexity in workflows with PCR
    • Automate library prep with validated scripts


    *Data on file.

  • KAPA RNA HyperPrep Kit Portfolio for RNA library
    KAPA RNA HyperPrep Kits offer single-day library prep, inclusive of RNA enrichment. The versatile portfolio includes solutions for mRNA enrichment, rRNA depletion, globin depletion, and custom depletion of high-expressors.*

    *Data on file.
    ...

  • KAPA RNA HyperPrep

    • Analyze prokaryotic or eukaryotic RNA
    • Use with degraded RNA, FFPE RNA, high-quality RNA, or previously enriched RNA
    • Detect low-abundance transcripts when paired with target enrichment

    KAPA RNA HyperPrep with RiboErase (HMR)

    • Analyze the whole transcriptome, including non-coding RNAs
    • Use with degraded RNA, FFPE RNA, or high-quality RNA
    • Customize RNA depletion (e.g., prokaryotic rRNA) with user-defined oligos

    KAPA RNA HyperPrep with RiboErase (HMR) Globin

    • Analyze the whole transcriptome, including non-coding RNAs
    • Use with blood-derived RNA, FFPE or degraded RNA, or high-quality RNA

    KAPA mRNA HyperPrep

    • Analyze the coding transcriptome
    • Use with high-quality total eukaryotic RNA
  • MagNA Pure 24 System
    The MagNA Pure 24 is a fully automated, easy-to-use clinical nucleic acid extraction system that provides low extraction-to-extraction variability*─ and now includes protocols for NGS sample prep.*

    *Data on file....

  • With the MagNA Pure 24 nucleic acid extraction system, you can:

    • Set up a run and walk away, relying on the MagNA Pure 24 to track samples and reagent inventory with a LIMS-compatible barcoded surveillance system
    • Choose from a list of pre-optimized protocols
    • Isolate nucleic acids for NGS library prep
    • Process 8 samples in less than 30 minutes with an expedited protocol, or process up to 24 samples in 70 minutes; preparation of samples for NGS requires longer run times
    • Simplify planning and setup with a single universal reagent kit for 8 pre-validated human sample types
    • Extract nucleic acids from multiple human sample types in the same run, including primary samples
    • Run samples with input volumes ranging from 200 μL to 4 mL
    • Reduce waste with resealable reagent kits
    • Use for in vitro diagnostic applications
  • LightCycler® Real Time PCR Systems
    The LightCycler® 96 and LightCycler® 480 Instruments provide the ideal combination of temperature homogeneity, data reproducibility, and intuitive analysis software*─ for a wide range of throughput needs and levels of user experience.*

    *Data on file.
    ...

  • The LightCycler® 96 Instrument: a simple-to-use qPCR system for rapid cycling of up to 96 samples

    • Eliminate edge effects with the innovative optical detection system, which simultaneously collects data from all samples
    • Choose from a wide range of probe formats
    • Run multiplexed samples
    • Simplify run setup with easy-to-use software, with easy import/export functions, post-run email notifications, remote run monitoring, and remote data analysis

    The LightCycler® 480 Instrument: a flexible-throughput qPCR system that can process up to 384 samples

    • Switch easily between 96- and 384-well blocks
    • Eliminate edge effects with the innovative optical detection system, which simultaneously collects data from all samples
    • Choose from a wide range of probe formats
    • Run multiplexed samples
    • Simplify run setup with easy-to-use software, with easy import/export functions, post-run email notifications, remote run monitoring, and integration into LIMS─ including robotic pipetting and loading
  • KAPA Library Quantification Kit
    KAPA Library Quantification Kits use qPCR to provide accurate, reliable library quantification across a wide range of library types, concentrations, fragment distributions and GC content.*

    *Data on file.
    ...

  • KAPA Library Quantification Kit

    • Improve the accuracy of library pooling with qPCR-based quantification
    • Optimize clustering by measuring only sequencing-competent libraries
    • Maximize sequencing capacity by avoiding over- or under-clustered flow cells

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