Breath Explor Sampling Device
Non-invasive sampling of aerosol particles in breath
DPPC, PC16:0/16:0 is a characteristic component of surfactant from distal parts of the lung, that are trapped in the 3 collectors of the BE device by impaction
The amount of DPPC is correlated to the mass of captured particles
Particles from 12 normal breaths are sufficient material to perform the analysis of drugs
The collected specimen of aerosol particles is different from an exhaled breath condensate
For diagnosis, exhaled breath offers a unique possibility, being simple and non-invasive, exhaled breath collection can easily be performed on large groups of healthy individuals and respiratory patients, thus providing enough power for case control omics studies designed for discovery of new biomarker candidates
Exhaled breath sampling is well suited for repeated sampling, opening up for unbiased hypothesis-generating longitudinal studies in the respiratory research, as well as follow-up targeted studies