Our Universal Peptide Traps can be used with any C18 nano-capillary column since they are a PSDVB polymeric monolith that has less retentivity than most C18 columns. By loading samples on to these traps in 2/97.9/0.1 ACN/H2O/TFA, even the most hydrophilic peptides can be trapped and the eluted with an ACN/0.1% Formic Acid in Water gradient and peptides will elute from the trap and refocus on the nano-capillary C18 column prior to gradient elution into the MS. To learn more about these traps, see a video at https://youtu.be/YxVyRtM-EWQ?si=5NtYwAGgKVr1oDiO.

PremierLCMS will be in booth # 244 at the ASMS Conference in Anaheim, CA, June 2-6, 2024. Please stop by to learn about our wide range of low cost ($500) premium nano-capillary columns and our universal peptide traps. We will also be introducing a partnership with MicrOmics Technologies in the development of products for MicroSampling, High Throughput Proteomics LCMS including Micro Tissue Samples and Single Cell Proteomics.

PremierLCMS provides custom premium columns to work with most Proteomics LCMS systems and applications. In addition to our full line of Reprosil and Magic HPLC and UHPLC packings, we can also custom pack any user provided materials. Although we generally do not recommend packed tip columns for flows greater than 200 nl/min (as emitters can be coupled to our columns in 2-10 nl of post column volume and provide post column voltage and replacement of fouled tips without loss of the column), we can do so with our custom column packing service upon request. We currently pack columns with ID's from 50-200 micron and lengths from 50 to 500 mm, but are open to other sizes as requested. All of our columns have a screened 1/16" female inlet (nanoViper compatible) and we offer a variety of column outlets to fit most LCMS platforms.