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Description

In this course several microextraction technologies will be discussed, namely solid phase microextraction (SPME), thin film microextraction (TFME) and needle trap devices (NT). The main principles of these techniques, different calibration methods, coupling strategies to GC, LC, and MS, method development steps, and advantages and disadvantages of each microextraction approach will be covered. In addition, during this short course, recent advances, developments and applications of each technique in fields such as forensic, environmental, food and flavor, and clinical analysis will be described. Other topics that will be covered involve the application of SPME for ligand-receptor binding and plasma protein binding studies, in vivo sampling of freely moving animals for pharmacokinetic and metabolomic studies, direct tissue analysis, and automation of SPME and related technologies in high-throughput format.

Register for this Short Course

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Course Outline

Introduction to solventless technologies
Theoretical principles of SPME, TFME and NT
Interfaces
Calibration
Method development
Automation
In vivo sampling
Drug and clinical analysis
Food, flavor and fragrance analysis
Environmental analysis
Direct coupling of different SPME formats with mass spectrometry

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Additional Info

Course Sub-Categories (Up to 5):
Analytical Metrology,Clinical Analysis,Environmental Analysis,Food,Gas Chromatography-Mass Spectrometry,Liquid Chromatography-Mass Spectrometry,Mass Spectrometry,Polymers

Proposal Number:
SC6738

Target Audience:
New and current SPME, TF-SPME and NTD users. The topics will interest analytical chemists, lab supervisors, scientists and industry regulators in the environmental, food, pharmaceutical, clinical, cosmetics and materials area. Adopters of the new GC-TF-SPME membranes should attend. In-vivo sampling may interest biologists, life scientists.