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Description

This course has been approved by the Royal Society of Chemistry (RSC) for purposes of Continuing Professional Development (CPD). This module looks at the method development process, the parameters to optimise and the order to do them in. How to validate the method and method optimisation are examined in detail. This knowledge is then put to the test in working out best techniques and methods in case studies.

Register for this Short Course

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Course Outline

Outline:
The method development process
Reviewing parameters for optimisation
How do I get my sample into GC?
How do I transport my sample through GC?
How do I transfer my sample onto column?
How do I separate my analytes?
How do I choose my column?
How do I detect my analytes?
Example case study & strategies used in its method development
Practical exercise: Choosing instrumentation & techniques - reviewing strategies for developing a method
Sampling processes (blanks, spikes)
Introduction to Method Performance
Linearity, limits of detection, limits of quantitation, accuracy, precision & robustness
Instrument Qualification & System Validation
Introduction to Accreditation

Learning outcomes
You will learn strategies for method development.
You will learn how to optimise for sensitivity or to reduce carryover.
You will learn how to break the method down into tasks.
You will learn about the parameters and how to optimise them for each method task.

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Additional Info

Course Sub-Categories (Up to 5):
Gas Chromatography,Gas Chromatography-Mass Spectrometry

Proposal Number:
SC7849

Target Audience:
Before attending this course you should have a good knowledge of gas chromatography and its techniques.