McCormick Place | Chicago, Illinois, USA
March 1 - 5, 2020

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The biggest party, the biggest night of the week, and the biggest opportunity to brand your company. The Pittcon Party will take place Wednesday evening at the Museum of Science and Industry. It will be a night to remember – and a night for attendees to remember you!

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Separations: Fundamentals of Advanced Gel Permeation & Size Exclusion Chromatography Detection

  • Room: Short Course Office S100C
  • Session Number: SC1265
Tuesday, March 03, 2020: 1:00 PM - 5:00 PM
Duration:1/2 Day Course


Carrie Schindler
Malvern Panalytical Inc.


This ½ day course covers the theoretical and practical principles of GPC & SEC. We will discuss how light scattering overcomes the limitations of column calibration to provide a direct measurement of ‘absolute’ molecular weight, irrespective of the sample’s chemistry, composition, and structure. This course will discuss the principles behind the different advanced detectors and how sample molecular weight and other parameters can be measured. We will also discuss practical aspects of making high quality GPC/SEC measurements and generating quality results. Finally, we will look at a series of application examples to see how these measurements can be applied to a wide range of applications and samples types.


Attendee Registration Exhibitor Registration

Learning Objectives

(15min) Introduction & Course Objectives: What is advanced GPC/SEC?
(30min) Fundamental and Limitations of the Conventional/single-detector GPC/SEC
(30min) Principles of molecular weight measurements by light scattering
(30min) Introduction to intrinsic viscosity, its measurement and meaning
(15min) Coffee/Tea Break
(45min) Practical considerations of multi-detector GPC/SEC measurements
(45min) Case Studies of Applications in Polymers, Biopolymers & Proteins
(30min) Practical Take Home Messages, Question and Answer Session

Additional Info

Target Audience:
Those with some general practical GPC or SEC experience who want to maximize the value obtained from their existing advanced detectors and those who are considering the potential benefit of adding such to their chromatography characterization portfolio: - Scientists, R&D personnel - Laboratory Technicians - Quality assurance and quality control staff

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