Musculoskeletal Disorders: Cause and Cures

  • Room: Versailles 1-2
  • Session Number: Keynote 2
Wednesday, November 03, 2021: 9:00 AM - 10:00 AM


Mary F. Barbe
Anatomy and Cell Biology Professor
Temple University School of Medicine


Musculoskeletal disorders are the major source of compensable work-related injuries affecting American workers.  Ergonomists often deal with injured or high-risk workers and they design strategies to prevent or mitigate such injuries. For many years we have known the risk factors of posture, load, repetition and stress, but are all of these equally important risks and how do these risks result in an actual injury? For the past two decades, Dr. Barbe has conducted groundbreaking research into how and why musculoskeletal disorders can arise. In this presentation, she will describe her groundbreaking research that has elucidated pathways that can lead to injury and this knowledge can be used to define optimally effective prevention strategies. The combination of high repetition and high force appears to be the most injurious. The pros, cons and limitations of conservative interventions (rest, ergonomic task reduction, ibuprofen, and manual therapy) as well as more aggressive interventions (anti-connective tissue growth factor and neurokinin-1 receptor antagonist treatments) will be discussed for the treatments of inflammation and fibrosis for the purpose of providing restorative repair.